No; you can just know that Bluetooth, NFC, WiFi-management and VPN Android apps simply will not work, as those things are part of the underlying OS. Delegating control over them to the Android runtime in a way that appears somewhat complete would be hard if not impossible.
This limitation has always been there, and i don’t see it changing substantially.
(Well, NFC should be toggle-able, but it probably is not prioritized)
I think this is the primary thread for this question: Bluetooth Support in Android