Can I run more than once simultaneously a native or / and android app with different settings?

I have few apps that I would like to run more than once simultaneously with different settings, like it was a different app (ex. a chat app, one for server A and the second one for server B)

Is there any simple way I could do it? I want it for native and android apps.

Thank you in advance

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While this is technically possible (e.g. the Terminal app can launch separate windows, and some apps have support for multiple accounts), I know of no app which combines these features though.

would it be possible for Android app if you have both AD and waydroid installed, it would be like 2 andoid instances. the overhead would be a huge drain, and AD plus waydroid installs would probably interfere with each other though.